Difference between Shut Up and Of Course

SHUT UP vs OF COURSE: ADJECTIVE

I don't believe it!, no way!
Of a person, to stop talking or (of a person or thing) making noise.
To put (an object) in a secure enclosed place.
To enclose (a person, animal or thing) in a room or other place so that it cannot leave.
To terminate (a business).
To close (a building) so that no one can enter.
Place in a place where something cannot be removed or someone cannot escape
Cause to be quiet or not talk
Refuse to talk or stop talking; fall silent

Asserts that the associated phrase should not be argued, particularly if it is obvious or there is no choice in the matter.
Acknowledges the validity of the associated phrase.
Indicates enthusiastic agreement.
As might be expected

Button up, Belt up, Dummy up, Lock away, Hush up, Still, Lock, Hush, Silence, Quieten, Put away, Close up, Lock in, Lock up, Be quiet

Each other, Not only, For sure, Move on, Other than, Too bad, Any more, Just as, No longer, Too much, So much, As well, After all, Naturally, Course

Confined, Lock away, Hush up, Dummy up, Clam up, Button up, Belt up, Still, Lock, Hush, Silence, Quieten, Close up, Lock in, Lock up

Go on, Paying attention, Used to, Each other, For sure, Move on, Other than, Too bad, Any more, Just as, No longer, Too much, So much, As well, Course

They must either put up or shut up.
His favorite sayings, back up, drop it, shut up.
Russia tells BRD, US, put up or shut up.
You told me to put up or shut up.
She shelf boston put up or shut up reficar.
The three marks of a good preachers are these: He stands up, speaks up, and knows when to shut up!
Saudi Arabia is a totalitarian state where my daughters are locked up, wrapped up and shut up.
Shut up, shut up, and take everything, disembodied code voice, take everything!
Poor women in psychological research: Shut up and shut out.
Shut up, dammit, all of you just shut UP!

And you should push back, legally, of course!
Of course, a dishwasher is also super convenient.
Pathologist has to do a postmortem, of course.
Of course, the Ranking Member has raised issues.
This is, of course, a very healthy development.
We of course also want to explain why.
Of course this is easier said than done.
There are, of course, many other universities application.
The course description and schedule of meetings must be consistent with the number of course credits proposed.
Well, drug users, of course, of course are smart.