Difference between Give Up and Resign

GIVE UP vs RESIGN: NOUN

To relinquish; to abandon.
To sign back; to return by a formal act; to yield to another; to surrender; -- said especially of office or emolument. Hence, to give up; to yield; to submit; -- said of the wishes or will, or of something valued; -- also often used reflexively.
To commit to the care of; to consign.

Admit defeat
Stop maintaining or insisting on
Of ideas or claims
Lose (something) or lose the right to (something) by some error, offense, or crime

To sign again.
To withdraw, as a claim; give up; abandon.
To yield or give up in a confiding or trusting spirit; submit, particularly to Providence.
To submit without resistance; yield; commit.
To intrust; consign; commit to the care of.
Synonyms To abandon, renounce, abdicate. Resign differs from the words compared under forsake in expressing primarily a formal and deliberate act, in being the ordinary word for giving up formally an elective office or an appointment, and in having similar figurative use.
To submit one's self; yield; endure with resignation.
To give up an office, commission, post, or the like.
To assign back; return formally; give up; give back, as an office or a commission, to the person or authority that conferred it; hence, to surrender; relinquish; give over; renounce.

Forgo, Stop, Discontinue, Spare, Render, Free, Surrender, Give, Forfeit, Quit, Abandon, Renounce, Drop out, Throw in, Lay off

Surrender, Demit, Withdraw, Quitting, Abdicate, Relinquish, Quits, Retire, Quit, Resignation, Give up, Reconcile, Submit, Renounce, Vacate

Cease, Leave, Vacate, Stop, Spare, Render, Free, Surrender, Give, Forfeit, Quit, Abandon, Drop out, Throw in, Lay off

Forsake, Forego, Abandon, Dismiss, Leave, Surrender, Quitting, Quits, Retire, Quit, Resignation, Give up, Reconcile, Submit, Vacate

Give Up Changes Made by Designated Give Ups to Affiliates and Back Office Agents.
Dribble, trickle, fall in quish, abandon, forswear, give up, give drops.
If we give up a right in one situation, we do not give up the same right in other situations.
If we give up any of our rights in one situation, we do not give up the same right in another situation.
Nothing save arches and if parents and teachers give up on there teens, they may feel even less motivated and give up on themselves.
Never give up: Sports teaches you to never give up.
No matter how you feel, get up, dress up, show up and never give up.
We give up, in a certain sense, we give up that classical notion of virtue.
If friends or family members want to give up, too, suggest to them that you give up together.
Give up privacy give up liberty and freedom.

Tuesday he was ready to resign if asked.
Today is no day to resign in hopelessness.
The director is under increasing pressure to resign.
Jeff Bezos to resign from the position of.
Eventually, she was forced to resign as principal.
Both men decided to resign if Trump persisted.
You are ready to resign the old one.
Is it better to get fired or resign?
She was so pissed, I think she may resign, pissed, so pissed she may resign.
Employees who resign from Vanderbilt are responsible for providing appropriate written notice of their intent to resign.